Figure 4: Actin network disruption leaves cores intact but hampers core oscillations. | Nature Communications

Figure 4: Actin network disruption leaves cores intact but hampers core oscillations.

From: Interplay between myosin IIA-mediated contractility and actin network integrity orchestrates podosome composition and oscillations

Figure 4

(a) Cells were seeded on glass coverslips and stimulated for 20 min with 2.5 μg ml−1 cytoD. Cells were subsequently fixed and stained with Texas Red-conjugated phalloidin to visualize actin. Representative images are shown. Scale bar, 5 μm. (b) Actin levels, visualized by Lifeact-RFP, versus time of randomly selected podosome cores. The arrow indicates the time point of cytoD stimulation. Data are normalized to the average intensity.

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