Table 1 Comparison of the calculated reaction energetics (kcal mol−1) for different possible protonation states involved in GTP hydrolysis by EF-Tu on the ribosome.
From: Energetics of activation of GTP hydrolysis on the ribosome
Mechanism |
|
|
|
|---|---|---|---|
| −110.2±1.7 | −127.7±0.2 | +17.5 |
| −0.9±0.2 | +2.8±0.1 | −3.7 |
| +10.5±1.3 | +2.8±0.1 | +7.7 |
| +18.6±1.0 | +2.8±0.1 | +15.8 |
| −26.6±1.1 | −23.2±0.1 | −3.4 |
| −22.5±0.2 | −23.2±0.1 | +0.7 |
