Figure 5: D-OH recognition by D14.
From: Molecular mechanism of strigolactone perception by DWARF14
(a) Side view of D-OH bound to D14. D-OH and the surrounding residues are shown as a stick model along with the 2Fo−Fc electron density coloured in blue and purple, respectively. (b) Binding site of D-OH. The residues surrounding D-OH are represented by a stick-and-sphere model. The dashed line shows a hydrogen bond between D-OH and the indole amine of Trp205. (c) Plug-like binding of D-OH to the catalytic cavity of D14. D-OH is shown using a sphere representation. (d) Superposed structure of apo and D-OH-bound D14. The crystal structures of apo and D-OH-bound D14 are shown as pink and yellow ribbon diagrams, respectively. D-OH and its surrounding residues are represented by stick diagrams. Phe245 is the only residue that moves (1.3 Å) towards D-OH.
