Figure 5: Single-molecule analysis suggests partial or incomplete modification of specific sites with PT in E. coli B7A.
From: Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences
(a) The kinetic signal average over all molecules at a selected genomic position showing a strong PT kinetic signal is shown on the left for E. coli B7A, with IPD ratio plot examples from single molecules underlying this average, which show between none and full PT-modification signals, are shown on the right. (b) The kinetic signal average over all molecules at a selected genomic position for which there was no detectable PT kinetic signal is shown on the left for E. coli B7A, with IPD ratio plot examples from single molecules underlying this average, which show the presence of some molecules with a PT modification, are shown on the right.
