Table 1 RegulomeDB predictions for allele-biased germline variants in somatically altered regulatory elements.
SNP* | Bias | Nearest gene(s) | Score | Bound protein | eQTL†|
|---|---|---|---|---|---|
rs10184180 | + | ID2 | 2b | PAX5 | — |
rs7556712 | − | CAPN10 | 2b | CTCF, HNF4A | — |
rs1566347 | + | SORBS2 | 2a | FOXA1, FOXA2, HEY1, HNF4G, EP300, TBP, HNF4A | — |
rs577388 | + | AK024998 | 1f | MAFF | C6orf160 |
rs4709360 | + | ZDHHC14 | 1a | ELF1, HNF4A, HNF4G, TAF1, CEBPB, CDX2, HNF4A, FOXA1, EP300, RAD21, RXRA, SP1, JUND, MAFF, MAFK, RFX5, TCF4 | ZDHHC14 |
rs7455225 | − | CLDN4 | 1f | CTCF, RAD21, GATA2 | WBSCR27 |
rs4458741 | − | CLDN4 | 2b | CDX2, HNF4A, JUND, SP1, FOXA1, EP300, TBP | — |
rs4148682 | + | CFTR | 2b | SUZ12 | — |
rs16899037 | + | FER1L6 | 2b | EGR1 | — |
rs16938533 | + | MIR31HG, MTAP | 2b | STAT3, FOS, TBP, TCF4, EP300, GATA2, NR3C1, JUN, JUND | — |
rs4307419 | + | MIR31HG, MTAP | 2b | STAT3, FOS, TBP, TCF4, EP300, GATA2, NR3C1, POLR2A, JUN, JUND | — |
rs114596416 | + | KCNE3 | 2b | ZNF263, CDX2 | — |
rs8036737 | + | RPUSD2, CASC5 | 2c | SP1, NFYA, NFYB, FOS | — |
rs3744942 | + | SERPINB5 | 2b | POLR2A | — |
rs2659104 | + | KLK1 | 1f | POLR2A | KLK1 |
rs6012888 | + | AK307192 | 2b | GABPA | — |
