Figure 3: Stathmin phosphorylation is essential for synaptic plasticity. | Nature Communications

Figure 3: Stathmin phosphorylation is essential for synaptic plasticity.

From: Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and disrupted in ageing

Figure 3

(a) Input–output relationship of perforant path to dentate gyrus synaptic responses from WT and mutant mice (n=4, 6 slices). (b) Deficient perforant path to dentate gyrus LTP in Stat4A mice (n=4, 6 slices). (c) Input–output relationship of Schaffer Collateral to CA1 (SC-CA1) synaptic responses from WT and Stat4A mice. No effect is found on the relationship between stimulus strength and the size of postsynaptic response (input–output relationship). (d) Stat4A mice show normal LTP at SC-CA1 synapses. Averaged field EPSP data (n=4, 5 slices). *P<0.05 versus WT mice. Data are expressed as mean±s.e.m.

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