Figure 3: De novo TBR1 truncating mutations abolish transcriptional repression activity. | Nature Communications

Figure 3: De novo TBR1 truncating mutations abolish transcriptional repression activity.

From: De novo TBR1 mutations in sporadic autism disrupt protein functions

Figure 3

Luciferase reporter assays for transcriptional regulatory activity of TBR1 variants in HEK293 cells. Values are expressed relative to the control. (***P<0.001, **P<0.01; NS, not significant when compared with WT TBR1). The mean±s.e.m. of three independent experiments performed in triplicate is shown.

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