Figure 1: Conformational states of rhodopsin analyzed in this study.
From: Constitutive phospholipid scramblase activity of a G protein-coupled receptor
The cartoon representations show the cytoplasmic face of the proteins: (a) inverse agonist-bound rhodopsin, (b) agonist-bound metarhodopsin II, (c) inactive and (d) active forms of the apoprotein opsin. The N2C/D282C double mutation confers thermostability, and the M257Y mutation generates a mimic of metarhodopsin II.
