Figure 7: Enrichment of Nr2f2 in Anf promoter region in Nr2f2mutant rats. | Nature Communications

Figure 7: Enrichment of Nr2f2 in Anf promoter region in Nr2f2mutant rats.

From: Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension

Figure 7

Chromatin immunoprecipitation (ChIP) was conducted using heart tissue lysate from wild-type hypertensive (n=3) and Nr2f2mutant rats (n=3) with an anti-Nr2f2 antibody (Nr2f2-Ab1, Abcam) or control IgG antibody (Cell signaling). ChIP enrichment at the Anf locus was quantified by qPCR and normalized to haemoglobin (Hbb) promoter amplification, which was used as a negative control. *P<0.05.

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