Figure 5: Analysis of tumour metastases detected by MRI and cryo-imaging.
From: MRI detection of breast cancer micrometastases with a fibronectin-targeting contrast agent
The (a) size of the given metastatic tumours in different tissues from mice tumour model of intracardiac injection, (b) their representative cryo-images, and (c) pre-injection MRI, 25 min post-injection MRI and subtraction images of the pre-injection and post-injection MRI are shown (tumours are indicated by arrows; all scale bars, 1 mm). (d) The contrast enhancement ratios of metastases in different tissues, r=Signalpost-injection/Signalpre-injection. The mean±s.d. were calculated from the tumours (n=3–6) in different mice imaged by CREKA-Tris(DOTA)3-enhanced MRI (*P<0.05, **P<0.01, Student’s t-test).
