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TranscriptSNPView: a genome-wide catalog of mouse coding variation

Nature Genetics volume 38, page 853 (2006)Cite this article

To the Editor:

With the recent release of the genome-wide sequence for multiple inbred mouse strains1, and with resequencing data for a large number of additional strains entering the public domain (http://www.niehs.nih.gov/crg/cprc.htm), we are one step closer to being able to identify the underlying genetic variants responsible for the trait characteristics that define each strain. Here, we describe a genome-wide catalog of coding variation in the mouse genome that was developed using an extensive collection of mouse DNA sequence reads, including those recently released by Celera, data from dbSNP2 and resequencing data generated by Perlegen Sciences for the US National Institute of Environmental Health Sciences (NIEHS). To display these data, we developed a new software tool, TranscriptSNPView, which has been integrated into the Ensembl Genome Browser to take advantage of the evolving mouse genome assembly and the latest Ensembl3 and Vega gene predictions4. TranscriptSNPView can be accessed via the Ensembl Genome Browser (http://www.ensembl.org/Mus_musculus/transcriptsnpview).

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Authors and Affiliations

  1. The Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, Cambridgeshire, UK

    Fiona Cunningham, Mark Griffiths, James Smith, Zemin Ning, Tony Cox, Pablo Marin-Garcin, Jane Rogers, Louise van der Weyden, Allan Bradley & David J Adams

  2. The European Bioinformatics Institute, Hinxton, CB10 1SD, Cambridgeshire, UK

    Daniel Rios, Paul Flicek, Javier Herrero & Ewan Birney

Authors
  1. Fiona Cunningham
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  2. Daniel Rios
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  3. Mark Griffiths
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  4. James Smith
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  5. Zemin Ning
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  6. Tony Cox
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  7. Paul Flicek
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  8. Pablo Marin-Garcin
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  9. Javier Herrero
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  10. Jane Rogers
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  11. Louise van der Weyden
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  12. Allan Bradley
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  13. Ewan Birney
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  14. David J Adams
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Corresponding author

Correspondence to Ewan Birney.

Supplementary information

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TranscriptSNPView: a genome-wide catalog of coding variation.

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Cunningham, F., Rios, D., Griffiths, M. et al. TranscriptSNPView: a genome-wide catalog of mouse coding variation. Nat Genet 38, 853 (2006). https://doi.org/10.1038/ng0806-853a

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