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Vaccine leads to memory loss

Nature Medicine volume 13, pages 248–250 (2007)Cite this article

A promising experimental vaccine strategy, just entering clinical trials, displays a deleterious effect in mice. Use of antibodies to CD40 seems to clamp down on the long-term ability of T cells to respond to antigen (pages 354–360).

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Figure 1: Pros and cons of artificial CD40 triggers.

Katie Ris

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Authors and Affiliations

  1. Division of Immunology, The Netherlands Cancer Institute, Plesmanlaan 121, CX, 1066, Amsterdam, The Netherlands

    John B A G Haanen & Ton N M Schumacher

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  1. John B A G Haanen
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  2. Ton N M Schumacher
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Haanen, J., Schumacher, T. Vaccine leads to memory loss. Nat Med 13, 248–250 (2007). https://doi.org/10.1038/nm0307-248

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