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From genomics to vaccines: Malaria as a model system

Abstract

Stephen Hoffman and colleagues from the Naval Medical Research Center and J. Craig Venter from TIGR propose a strategy for applying the wealth of information that will come from sequencing the entire genome of Plasmodium falciparum (the parasite that causes the fatal form of malaria) to the development of a malaria vaccine.

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Acknowledgements

The authors thank D. Doolan for critical reading of the manuscript. The work described was funded by Naval Medical Research and Development Command Work Units 61102AA0101BFX and 611102A0101BCX. The opinions expressed are those of the authors and do not reflect the official policy of the Department of the Navy, Department of Defense, or the U.S. government.

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Hoffman, S., Rogers, W., Carucci, D. et al. From genomics to vaccines: Malaria as a model system . Nat Med 4, 1351–1353 (1998). https://doi.org/10.1038/3934

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