Abstract
The sequencing of the Plasmodium falciparum genome should reveal new parasite protein targets for drug and vaccine development.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout
References
Wirth, D.F. & Cattani, J. Winning the war against malaria. Tech. Rev. 100, 52–61 (1997).
Gardner, M.J. et al. Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum. Science 282, 1126– 1132 (1998).
Weber, J.L. Interspersed repetitive DNA from Plasmodium falciparum. Molec. Biochem. Parasitol. 29, 117– 124 (1988).
Wang, R. et al. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science 282, 476–480 (1998).
DeRisi, J.L., Vishwanath, R.I. & Brown, P.O. Exploring the metabolic and genetic control of gene expression on a genomic scale. Science 278, 680–686 (1997).
Wodicka, L., Dong, H., Mittmann, M., Ming-Hsiu, H. & Lockhart, D.J. Genome-wide expression monitoring in Saccharomyces cerevisiae. Nat. Biotechnol. 15, 1359–1367 (1997).
Velculescu, V.E. et al. Characterization of the yeast transcriptome. Cell 88, 243–251 (1997).
Marton, M.J. et al. Drug target validation and identification of secondary drug target effects using DNA microarrays. Nature Med. 4, 1293–1301 (1998).
Winzeler, E.A. et al. Direct allelic variation scanning of the yeast genome. Science 281, 1194–1197 (1998).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Wirth, D. Malaria: A 21st century solution for an ancient disease. Nat Med 4, 1360–1362 (1998). https://doi.org/10.1038/3943
Issue date:
DOI: https://doi.org/10.1038/3943
This article is cited by
-
CytochromeP450 isoenzyme specificity in the metabolism of anti-malarial biguanides: molecular docking and molecular dynamics analyses
Medicinal Chemistry Research (2012)
-
A shotgun optical map of the entire Plasmodium falciparum genome
Nature Genetics (1999)