Table 2 Overview of items selected in round 1 and the results of the Delphi procedure

From: Adaptation of a difficult-to-manage asthma programme for implementation in the Dutch context: a modified e-Delphi

Name item

Percentage of participants that scored 5

Mean score

Selected a

Diagnosis and monitoring

 Explanation what is difficult-to-manage asthma

98%

6.3

Yes

 Identification of patients with difficult-to-manage asthma

93%

6.1

Yes

 What is the difference between difficult-to-manage asthma and severe asthma

90%

5.9

Yes

 Further insight into the potential consequences of a diagnosis of severe asthma (such as the use of biologicals, revalidation-therapy, high-altitude treatment.)

88%

5.7

Yes

 Has asthma been diagnosed according to the current guidelines

81%

5.8

Yes

 The role of comorbid diseases in asthma

76%

5.4

No

 Differential diagnosis of asthma and which potential concurrent diagnoses require further investigation/management

86%

5.6

Yes

 Which other tests should/could be performed other than symptoms and spirometry, to diagnose asthma

86%

5.3

Yes

 Role of blood eosinophils

62%

4.9

No

 Role of NT-BNP

36%

4.1

No

 Role of histamine-provocation

71%

5.1

No

 Role of FeNO

45%

4.5

No

 Role of pulmonary imagining

40%

4.1

No

 Role of the ACQ

83%

5.6

Yes

 Role of the AQLQ

48%

4.6

No

 Role of the RIC-MON 10

26%

3.7

No

 Role of spirometry

71%

5.3

No

 Role of different phenotypes of asthma

83%

5.7

Yes

 How to assess different phenotypes of asthma in a patient

86%

5.6

Yes

 Identification of patients with an increased risk of asthma exacerbations

90%

5.8

Yes

 Frequency of monitoring for the individual patient

83%

5.4

Yes

 Clear guidelines for referrals between primary and hospital care

86%

5.8

Yes

 Determining current control

88%

5.8

Yes

 Content of monitoring in the individual patient

90%

5.8

Yes

 Additional use of spirometry in patients with no symptoms and persistent obstruction

79%

5.3

No

 Additional use of spirometry in patients with a lot of symptoms and a normal lung function

79%

5.3

No

 Role of peak flow in daily monitoring

40%

4.0

No

 Identification of patients suitable for pulmonary rehabilitation

83%

5.5

Yes

 Determining general goals of treatment

74%

5.1

No

 Determining personal goals of treatment.

98%

6.0

Yes

Medication(-related) therapy

 Denominate central role-inhaled corticosteroids

90%

5.9

Yes

 Name common side-effects of different types of medication

93%

5.5

Yes

 Pharmacotherapy for specific subgroups: does comorbidity determine medication choices

86%

5.4

Yes

 Identification of suitable patients for LTRA

76%

4.9

No

 Role of inhalation instruction

90%

6.2

Yes

 Role of device type

88%

5.8

Yes

 Inventarisation of adherence

93%

6.0

Yes

 Role of particle size

62%

4.9

No

 Patient perceptions on benefits and necessity of medication

93%

6.0

Yes

Non-pharmacological management

 Follow-up of comorbidity

74%

5.0

No

 An asthma action plan for every asthma patient

71%

5.1

No

 An asthma action plan for every difficult-to-manage asthma patient

98%

6.2

Yes

 Recognition of causing agents of exacerbations

86%

5.7

Yes

 Effect of smoking on asthma

90%

6.0

Yes

 Role of passive smoking

86%

5.6

Yes

 Other types of drugs

69%

5.1

No

 Insight into aspecific irritants

95%

6.0

Yes

 Insight into allergens

97%

6.0

Yes

 Insight into occupational irritants

93%

5.8

Yes

 Insight into hobby-related irritants

83%

5.5

Yes

 Attention for physical activity

90%

5.8

Yes

 Role of weight

90%

5.8

Yes

 Identification of obstacles for adherence (social, financial, societal)

88%

5.7

Yes

 Recognition of stress-inducing factors

81%

5.5

Yes

 Self-management for all people with (difficult to manage) asthma

95%

6.0

Yes

 Identification of patients suited to different types of self-management: paper, online, real-life

83%

5.5

Yes

 Role of eHealth

64%

5.0

No

 How to make patients aware of asthma worsening events/behaviour

93%

5.7

Yes

 Education on asthma

86%

5.6

Yes

 Insight into the patients personal environment

90%

5.5

Yes

 Getting a patients’ environment involved in treatment

79%

5.3

No

 Knowledge about the relation between symptoms and work

88%

5.6

Yes

 Necessity of an individual care plan for all patients with (difficult to manage) asthma

83%

5.7

Yes

 Recognition and acceptance of personal limitations

88%

5.7

Yes

 Estimation of desire and potential for behavioural changes

88%

5.6

Yes

  1. Abbreviations: ACQ, asthma control questionnaire; AQLQ, asthma quality of life questionnaire; FeNO, fractional exhaled nitric oxide; LTRA, leucotriene receptor antagonist; NT-BNP, N-terminal brain natriuretic peptide; RIC-MON 10, Dutch questionnaire on symptom severity.
  2. a Yes if 80% of participants scored 5 on this item.