A prospective study of 229,119 men and 173,141 women (median follow-up 13.6 years) has shown that coffee consumption is not linked with increased risk of cardiovascular death. Indeed, after adjustment for various potential dietary and lifestyle confounders, higher coffee consumption was associated with lower mortality. In total, 8,127 individuals died from heart disease and 1,327 people died as a result of stroke. Compared with drinking no coffee, daily consumption of <1 cup, 1 cup, 2 or 3 cups, 4 or 5 cups, and ≥6 cups of coffee was associated with adjusted HRs for heart-disease-linked death of 0.93, 0.92, 0.86, 0.87, and 0.88, respectively (P value for trend = 0.03). Similarly, adjusted HRs for stroke-linked death were 0.99, 0.92, 0.84, 0.65, and 0.83, respectively (P value for trend = 0.003). Notably, the study does not provide any information on whether or not this association is causal.