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Risk factors

HDL-C levels not specific to cardiovascular mortality

Nature Reviews Cardiology volume 14, page 2 (2017)Cite this article

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Individuals with low (≤30 mg/dl) levels of high-density lipoprotein cholesterol (HDL-C), have higher cardiovascular and noncardiovascular mortality than individuals with intermediate levels of HDL-C. However, individuals with high levels of HDL-C (>70 mg/dl in men; >90 mg/dl in women) also have increased noncardiovascular morality. These findings come from an analysis of 631,762 individuals without previous cardiovascular conditions or severe comorbidities in the CANHEART cohort. “HDL-C level is a marker of poor general health and may not be an independent modifiable risk factor specifically for cardiovascular disease,” summarize the investigators.

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References

  1. Ko, D. T. et al. High-density lipoprotein cholesterol and cause-specific mortality in individuals without previous cardiovascular conditions: the CANHEART study. J. Am. Coll. Cardiol. 68, 2073–2083 (2016)

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  1. Dario Ummarino
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Ummarino, D. HDL-C levels not specific to cardiovascular mortality. Nat Rev Cardiol 14, 2 (2017). https://doi.org/10.1038/nrcardio.2016.186

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