Table 1 Baseline characteristicsa
From: Impact of vitamin D supplementation on adiposity in African-Americans
Characteristic | Vitamin D3 dose assignment (IU per day) | P-valueb | |||
|---|---|---|---|---|---|
Placebo | 1000 | 2000 | 4000 | ||
(n=81) | (n=81) | (n=83) | (n=83) | ||
Age, years, median (IQR) | 50.7 (44.1–58.0) | 51.1 (43.4–60.1) | 50.3 (43.5–58.3) | 51.3 (44.1–59.7) | 0.98 |
Sex, No. (%) | 0.72 | ||||
Male | 27 (33.3) | 22 (27.2) | 28 (33.7) | 29 (34.9) | |
Female | 54 (66.7) | 59 (72.8) | 55 (66.3) | 54 (65.1) | |
BMI, kgm−2, median (IQR) | 31.2 (26.5–35.9) | 30.5 (27.0–37.5) | 31.9 (26.2–36.9) | 31.4 (27.4–35.7) | 0.82 |
BMI <25 kgm−2, mean (s.d.) | 20.8 (2.2) | 23.3 (1.4) | 22.9 (1.4) | 21.9 (3.1) | |
No. (%) | 11 (13.5) | 11 (13.5) | 16 (19.2) | 10 (8.3) | |
BMI 25–29.9 kgm−2, mean (s.d.) | 27.0 (1.1) | 27.9 (1.5) | 27.6 (1.5) | 27.6 (1.5) | |
No. (%) | 25 (30.8) | 24 (29.6) | 21 (25.3) | 25 (30.1) | |
BMI >30 kgm−2, mean (s.d.) | 37.1 (5.9) | 37.6 (5.8) | 38.4 (6.2) | 36.6 (5.6) | |
25(OH)D <20 ng ml−1, No. (%) | 53 (65) | 50 (62) | 59 (71) | 53 (64) | 0.46 |
25(OHD) ng ml−1, median (IQR) | 15.1 (10.4–23.6) | 16.2 (11.0–22.7) | 13.9 (9.5–22.3) | 15.7 (11.0–23.3) | 0.63 |
Smoking status, No. (%) | 0.26 | ||||
Never | 33 (40.7) | 36 (44.4) | 33 (39.8) | 44 (53.0) | |
Past | 20 (24.7) | 16 (19.8) | 27 (32.5) | 20 (24.1) | |
Current | 28 (34.6) | 29 (35.8) | 23 (27.7) | 19 (22.9) | |
Frequency of exercise,c days per week, median (IQR) | 3.0 (0.5–5.0) | 3.0 (1.0–5.0) | 3.0 (0–5.0) | 3.0 (0–5.0) | 0.99 |
Dietary vitamin D intake, median (IQR) | 147.3 (71.4–262.8) | 162.5 (92.6–295.5) | 144.0 (58.0–265.1) | 198.1 (83.2–306.4) | 0.41 |
Dietary calcium intake, median (IQR) | 264.6 (177.7–600.8) | 419.4 (233.5–820.3) | 314.4 (178.2–632.0) | 425 (203.4–829.0) | 0.11 |
Regular multivitamin use,d No. (%) | 10(12) | 18(22) | 15(18) | 22(27) | 0.16 |
Regular vitamin D supplement use,d No. (%) | 8(10) | 6(8) | 2(2) | 8(10) | 0.45 |
Food, servings per week (median (IQR)) | |||||
Milk | 0.1 (0.1–0.3) | 0.1 (0.1–0.6) | 0.3 (0.1–0.6) | 0.3 (0.1–0.6) | 0.9 |
Soy milk | 0 | 0 | 0 | 0 | 0.41 |
Cheese | 0.3 (0.1–0.3) | 0.3 (0.1–0.3) | 0.3 (0.1–0.6) | 0.4 (0.1–0.6) | 0.58 |
Ice cream | 0.1 (0–0.1) | 0 (0–0.1) | 0.1 (0–0.3) | 0.1 (0–0.3) | 0.64 |
Yogurt | 0 (0–0.1) | 0.1 (0–0.3) | 0 (0–0.3) | 0.1 (0–0.3) | 0.03 |
Green leafy vegetables | 0.3 (0.1–0.6) | 0.3 (0.3–0.6) | 0.3 (0.1–0.6) | 0.3 (0.3–0.6) | 0.71 |
Dark fish | 0.1 (0–0.3) | 0.1 (0–0.1) | 0.1 (0–0.3) | 0.1 (0–0.3) | 0.52 |
Orange juice | 0.1 (0–0.3) | 0.1 (0–0.3) | 0.1 (0–0.3) | 0.1 (0–0.6) | 0.29 |
Cold cereal | 0.1 (0–0.3) | 0.1 (0–0.3) | 0.1 (0–0.3) | 0.1 (0–0.3) | 0.78 |
Post-menopausal hormone use, No. (%) | |||||
Yes | 0 | 0 | 0 | 1 (0.5) | 0.72 |
Regular calcium supplement use,d No. (%) | 7 (8.7) | 9 (11.1) | 7 (8.4) | 9(10.8) | 0.49 |
Regular aspirin use,e No. (%) | 4 (4.9) | 10 (12.3) | 5 (6.0) | 8 (9.6) | 0.23 |
Regular NSAID use,f No. (%) | 6 (7.4) | 10(12.3) | 10 (12.0) | 7 (8.4) | 0.73 |
Regular acetaminophen use, No. (%)e | 6 (7.4) | 6 (7.4) | 5 (6.0) | 5 (6.0) | 0.96 |
Marital status, married, No. (%) | 23 (28.4) | 30 (37.0) | 23 (27.7) | 24 (28.9) | 0.58 |
History of cancer, No. (%)g | 6 (7.4) | 0 | 3 (3.6) | 15 (4.6) | 0.032 |