Table 2 Effect of vitamin D supplementation on BMI and weight during the treatment (baseline to 3 months, mean (SE)) and 6 months after treatment
From: Impact of vitamin D supplementation on adiposity in African-Americans
Parameter, mean (SE) | Placebo | 1000 | 2000 | 4000 | 0–3 month change | P-value | 3–6 month change | P-value | 0–6 month change | P-value |
|---|---|---|---|---|---|---|---|---|---|---|
n ( at baseline) | 81 | 81 | 83 | 83 | ||||||
BMI, kg m −2 | ||||||||||
Baseline BMI | 31.85 (0.9) | 32.46 (0.91) | 32.96 (0.96) | 32.15 (0.81) | 0.01 (0.39) | 0.78 | 0.01 (0.04) | 0.71 | 0.01 (0.05) | 0.87 |
3 month BMI | 32.00 (0.9) | 32.41 (0.93) | 33.11 (0.96) | 32.28 (0.83) | ||||||
6 month BMI | 32.14 (0.92) | 32.50 (0.96) | 32.54 (0.96) | 32.02 (0.84) | ||||||
Difference BMI (0–3) | 0.15 (0.09) | −0.04 (0.11) | 0.15 (0.13) | 0.13 (0.12) | ||||||
Difference BMI (3–6) | −0.18 (0.10) | −0.19 (0.10) | 0.01 (0.11) | −0.14 (0.12) | ||||||
Difference BMI (0–6) | 0 (0.11) | −0.17 (0.16) | 0.02 (0.16) | −0.02 (0.15) | ||||||
Weight (wt), kg | ||||||||||
Baseline weight | 89.63 (2.44) | 89.40 (2.43) | 92.73 (2.73) | 89.54 (2.44) | 0.06 (0.24) | 0.81 | 0.12 (0.22) | 0.59 | 0.07 (0.29) | 0.8 |
3 month weight | 90.03 (2.50) | 89.29 (2.50) | 93.13 (2.71) | 89.90 (2.49) | ||||||
6 month weght | 201.22 (5.63) | 200.02 (5.62) | 203.23 (6.22) | 198.48 (5.71) | ||||||
Difference weight (0–3) | 0.41 (0.27) | −0.11 (0.30) | 0.39 (0.38) | 0.36 ( 0.36) | ||||||
Difference weight (3–6) | −1.05 (0.62) | −1.37 (0.60) | 0.02 (0.70) | −0.78 (0.73) | ||||||
Difference weight (0–6) | 0.07 (0.67) | −1.37 (0.60 ) | 0.01 (0.96) | −0.02 (0.94) | ||||||
25(OH)D, ng ml −1 | ||||||||||
Baseline 25(OH)D | 17.07 (1.03) | 17.33 (1.00) | 16.12 (0.98) | 17.79 (0.98) | 7.75 (0.39) | <0.0001 | −4.74 (0.32) | <0.0001 | 3.04 (0.31) | <0.0001 |
3 month 25(OH)D | 14.23 (0.96) | 28.12(1.11) | 35.48 (1.21) | 47.30 (1.22) | ||||||
6 month 25(OH)D | 19.07 (1.0) | 22.26 (0.96) | 26.77 (1.02) | 31.46 (0.81) | ||||||
Difference 25(OH)D(0–3) | −2.58 (0.66) | 11.01(1.22) | 19.21 (1.21) | 29.79 (1.29) | ||||||
Difference 25(OH)D(3–6) | 4.78 (0.77) | −5.80 (1.10) | −9.20 (0.91) | −15.71 (0.93) | ||||||
Difference 25(OH)D(0–6) | 1.83 (0.86) | 5.02 (0.87) | 10.29 (0.95) | 13.81 (0.99) | ||||||