Figure 1
Effect of anthelmintic treatment on adiponectin, leptin, resistin, and leptin to adiponectin ratio in soil-transmitted helminth (STH)-infected and uninfected subjects. The effect of anthelmintic treatment on adiponectin (ADI), leptin (LEP), resistin (RES) and leptin to adiponectin ratio (L/A) in (a) STH-uninfected and (b) STH-infected subjects, as assessed by microscopy, are presented as proportion of changes (95% CI) between pre and post treatment in the albendazole group compared with the placebo group which is set to zero. Adiponectin, leptin, resistin and L/A ratio were log-transformed for analysis. Analysis was performed on 1183 subjects, after excluding 12 subjects with diabetes. Treatment effect estimates were the regression coefficient (β) obtained from mixed models indicating changes in log (ADI or LEP or RES or L/A); the treatment effect factors (10β) are proportional instead of additive. Thus, treatment effect factors indicate the proportional change in each variable in comparison to the placebo group. *P<0.05.
