Table 1 Comparison of demographic and clinical characteristics between cases (men with a BMI30 kg m−2) and controls (men with a BMI <25 kg m−2) at Mayo Rochester and Mayo Florida

From: Obese men have more advanced and more aggressive prostate cancer at time of surgery than non-obese men after adjusting for screening PSA level and age: results from two independent nested case–control studies

 

Mayo Rochester

Mayo Florida

 

ControlBMI<25 (N=1244)

CaseBMI30 (N=1817)

Total (N=3061)

ControlBMI<25 (N=133)

CaseBMI30 (N=206)

Total (N=339)

Surgery Year

 2000–2002

247 (19.8%)

498 (27.4%)

745 (24.3%)

N/A

N/A

N/A

 2003–2005

363 (29.1%)

486 (26.7%)

849 (27.7%)

N/A

N/A

N/A

 2006–2009

634 (51.1%)

833 (45.9%)

1467 (47.9%)

104 (78.1%)

148 (71.8%)

252 (74.3%)

 2010–2011

N/A

N/A

N/A

29 (21.9%)

58 (28.2%)

87 (25.7%)

Surgery Type

 RRP

991 (79.7%)

1419 (78.1%)

2410 (78.7%)

47 (35.3%)

93 (45.1%)

140 (41.3%)

 Laparoscopic

253 (20.3%)

398 (21.9%)

651 (21.3%)

86 (64.7%)

113 (54.9%)

199 (58.7%)

Age at Surgery

 Mean (SD)

61.9 (6.63)

61.8 (6.16)

61.8 (6.36)

63.3 (7.5)

61.9 (7.2)

62.4 (7.3)

 Median

62.0

62.0

62.0

64.2

62.7

63.0

 Q1, Q3

56.5, 67.0

57.0, 66.0

57.0, 66.0

57.7, 68.9

57.5, 66.9

57.6, 67.5

 Range

(50.0–80.0)

(50.0–78.0)

(50.0–80.0)

(29.9–78.4)

(43.1–78.6)

(29.9–78.6)

Age group

 <60

495 (39.8%)

685 (37.7%)

1180 (38.5%)

40 (30.1%)

71 (34.5%)

111 (32.7%)

 60X<70

566 (45.5%)

915 (50.4%)

1481 (48.4%)

72 (54.1%)

111 (53.9%)

183 (54.0%)

 70+

183 (14.7%)

217 (11.9%)

400 (13.1%)

21 (15.8%)

24 (11.7%)

45 (13.3%)

Pre–op PSA

 Mean (SD)

7.0 (6.24)

7.7 (13.30)

7.4 (11.00)

6.8 (6.0)

6.6 (6.1)

6.7 (6.0)

 Median

5.6

5.7

5.6

5.2

5.4

5.3

 Q1, Q3

4.1, 7.9

4.2, 8.0

4.1, 8.0

4.0, 7.6

4.2, 7.1

4.1, 7.3

 Range

(0.7–93.6)

(0.1–467.0)

(0.1–467.0)

(0.1–40.7)

(0.1–54.3)

(0.1–54.3)

PSA group

 <2

56 (4.5%)

86 (4.7%)

142 (4.6%)

10 (7.5%)

14 (6.8%)

24 (7.1%)

 24

241 (19.4%)

307 (16.9%)

548 (17.9%)

22 (16.5%)

28 (13.6%)

50 (14.7%)

 46

399 (32.1%)

578 (31.8%)

977 (31.9%)

49 (36.8%)

76 (36.9%)

125 (36.9%)

 610

360 (28.9%)

559 (30.8%)

919 (30%)

34 (25.6%)

64 (31.1%)

98 (28.9%)

 10+

188 (15.1%)

287 (15.8%)

475 (15.5%)

18 (13.5%)

24 (11.7%)

42 (12.4%)

BMI at surgery

 Mean (SD)

23.4 (1.29)

33.5 (6.19)

29.4 (6.93)

23.3 (1.4)

33.4 (3.0)

29.5 (5.5)

 Median

23.7

32.4

30.6

23.7

32.7

30.7

 Q1, Q3

22.6, 24.4

31.0, 34.5

24.1, 33.0

22.5, 24.4

31.2, 34.9

24.1, 33.4

 Range

(16.2–25.0)

(30.0–208.7)

(16.2–208.7)

(18.5–25.0)

(30.0–45.5)

(18.5–45.5)

BMI group

 <25

1244 (100%)

0 (0%)

1244 (40.6%)

133 (100.0%)

0 (0.0%)

133 (39.2%)

 3035

0 (0%)

1430 (78.7%)

1430 (46.7%)

0 (0.0%)

156 (75.7%)

156 (46.0%)

 3540

0 (0%)

309 (17%)

309 (10.1%)

0 (0.0%)

42 (20.4%)

42 (12.4%)

 40+

0 (0%)

78 (4.3%)

78 (2.5%)

0 (0.0%)

8 (3.9%)

8 (2.4%)

  1. Abbreviations: BMI, body mass index; RRP, radical retropubic prostatectomy.