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References
Goldmuntz E, Emanuel BS 1997 Genetic disorders of cardiac morphogenesis. Circ Res 80: 437–443
Jerome AL, Papaioannou V 2001 DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1. Nature Genet 27: 286–291.
Lindsay EA, Vitelli F, Su H, Morishima M, Huynh T, Pramparo T, Jurecic V, Ogurinu G, Sutherland H, Scambler P, Bradley A, Baldini A 2001 Tbx1 haploinsufficiency in the DiGeorge syndrome region causes aortic arch defects in mice. Nature 410: 97–101
Merscher S, Funke B, Epstein JA, Heyer J, Puech A, Lu MM, Xavier RJ, Demay MB, Russell RG, Factor S, Tokooya K, Jore BS, Lopez M, Pandita RK, Lia M, Carrion D, Xu H, Schorle H, Kobler JB, Scrambler P, Wynshaw-Boris A, Skoultchi AI, Morrow BE, Kucherlapati R 2001 TBX1 is responsible for cardiovascular defects in Velo-Cardio-Facial/DiGeorge syndrome. Cell 104: 619–629
Hatcher CH, Kim MS, Basson CT 2000 Atrial form and function: lessons from human molecular genetics. Trends Cardiovasc Med 10: 93–101
Guris DL, Fantes J, Tara D, Druker BJ, Imamoto A 2001 Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge syndrome. Nature Genet 27: 293–298
Goldmuntz E, Clark BJ, Mitchell LE, Jawad AF, Cuneo BF, Reed L, McDonald-McGinn D, Chien P, Feuer J, Zackai EH, Emanuel BS, Driscoll DA 1999 Frequency of 22q11 deletions in patients with conotruncal defects. J Am Coll Cardiol 32: 492–498
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Kim, MS., Basson, C. Wrapping Up DiGeorge Syndrome in a T-box?. Pediatr Res 50, 307–308 (2001). https://doi.org/10.1203/00006450-200109000-00001
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DOI: https://doi.org/10.1203/00006450-200109000-00001