Fig. 3: Main mechanisms of action employed by Il9-modulating transcription factors.
From: Locus of (IL-9) control: IL9 epigenetic regulation in cellular function and human disease
IL-9-regulating transcription factors (TFs) are reported to regulate IL-9 expression via several mechanisms of action. These include direct binding, modulation of accessibility, histone modification, and induction or repression of other Il-9-modulating TFs. In this schematic, the curved arrows indicate that a TF directly targets—or binds to—the Il9 locus. Activating or inhibitory effects on other proteins are shown by straight arrows or lines, respectively.
