Fig. 4: The immune microenvironment was altered following CD169+ macrophage depletion.

a The frequency of B cells, NK cells, T cells, neutrophils and Ly6C+ monocytes in CD45+ cells. b–g Immunohistochemical staining and quantification of CD19 (b), CD3 (c), NKp46 (d), MPO (e), Ly6C (f) and F4/80 (g) positive cells. h, The frequency of Th1, Th2, Th17, Treg and CTL. Results are expressed as mean ± standard error. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.