Fig. 2: TFs regulate ferroptosis process and the crosstalk with it and other forms of cell death. | Experimental & Molecular Medicine

Fig. 2: TFs regulate ferroptosis process and the crosstalk with it and other forms of cell death.

From: Ferroptosis-associated transcriptional factors in neurological diseases: molecular mechanisms and therapeutic prospects

Fig. 2

a The general scheme of TFs regulating ferroptosis in CNS. Overview of the role of TFs in regulating ferroptosis through three following aspects: iron accumulation, antioxidant defense and LPO. The relevant TFs for each mechanism are listed. b TFs on the crosstalk between ferroptosis and other forms of cell death. The illustration shows the interaction between ferroptosis and other types of cell death, such as apoptosis, pyroptosis, autophagy, necroptosis and cuproptosis. ⟶, activation; ⊣, inhibition. Figure created with BioRender.com.

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