Table 1 Characteristics of the study participants in gestational week 28 ± 2 (otherwise stated).

From: Epigenome-wide association study of DNA methylation in maternal blood leukocytes with BMI in pregnancy and gestational weight gain

 

Europeans

South Asians

Participants, n

303

164

Age in whole years, mean (SD)

30.6 (4.5)

28.7 (4.5)

Height in cm, mean (SD)

167.4 (5.7)

159.8 (5.8)

Pre-pregnancy BMI (kg/m2), mean (SD)

25.2 (4.8)

24.4 (4.1)

Body mass index (kg/m2), mean (SD)

27.7 (4.8)

26.9 (4.1)

Gestational weight gain in kg, mean (SD)

14.5 (6.4)

12.6 (5.6)

Total fat mass percentage, median [IQR]

29.5 [28.4, 30.6]

26.3 [25.0, 27.6]

Truncal fat mass percentage, median [IQR]

15.8 [15.2, 16.4]

14.0 [13.2, 14.9]

Gestational diabetes mellitus, n (%)

73 (23.9)

68 (41.5)

HbA1c, mmol/mol (SD)

32 (0.3)

34 (0.3)

Serum fasting glucose, mmol/L (SD)

4.4 (0.5)

4.5 (0.5)

Serum fasting insulin, pmol/L, median [IQR]

48.00 [33.0, 70.00]

72.00 [57.0, 102.5]

Serum fasting C-peptide, pmol/L, median [IQR]

708.0 [558.0, 900.0]

855.5 [688.8, 1078.2]

HOMA-IR, percentage, mean (SD)

1.5 [1.2, 1.9]

1.8 [1.5, 2.3]

HOMA-B, percentage, median [IQR]

173.5 [151.3, 199.5]

179.6 [154.9, 207.9]

Serum fasting total cholesterol, mmol/L, mean (SD)

6.4 (1.1)

6.0 (1.0)

Serum fasting HDL, mmol/L, mean (SD)

1.9 (0.4)

1.9 (0.4)

Serum fasting LDL, mmol/L, mean (SD)

3.7 (1.0)

3.3 (0.9)

Serum fasting TAG, mmol/L, mean (SD)

2.0 (0.7)

2.0 (0.6)

Leptin, µg/L, median [IQR]

1.6, [1.0, 2.5]

2.3 [1.5, 3.3]

Systolic blood pressure (mmHg), mean (SD)

106.9 (9.6)

101.2 (8.7)

Diastolic blood pressure (mmHg), mean (SD)

68 (7.1)

66 (7.0)

Nulliparous, n (%)

156 (51.5)

66 (40.2)

Smoking status, n (%)

  

 Current

19 (6.2)

0 (0.0)

 3 months pre-pregnancy

79 (25.9)

2 (1.2)

 Former

87 (28.5)

10 (6.1)

 Never

120 (39.3)

152 (92.7)

  1. Data are mean (SD) for normally distributed variables and median [IQR] for non-normal variables.
  2. Data are mean (95% CI) for normally distributed variables and median [IQR] for non-normal variables.
  3. CI confidence interval, IQR interquartile range, BMI body mass index, HbA1c glycosylated hemoglobin A1c, HOMA-IR homeostatic model assessment for insulin resistance, HOMA-B homeostasis model assessment of beta-cell function, HDL high-density lipoprotein, LDL low-density lipoprotein, TAG triacylglycerol.