Fig. 1: Stratification of biomarker-associated genetic instruments by their biological effects on established downstream traits. | International Journal of Obesity

Fig. 1: Stratification of biomarker-associated genetic instruments by their biological effects on established downstream traits.

From: Likely causal effects of insulin resistance and IGF-1 bioaction on childhood and adult adiposity: a Mendelian randomization study

Fig. 1: Stratification of biomarker-associated genetic instruments by their biological effects on established downstream traits.

A Fasting insulin associated genetic instruments were filtered by their direction of effect on fasting glucose. B IGF-1 associated genetic instruments were filtered by their direction of effect on childhood height. IGF-1 insulin-like growth factor-1, SNPs single nucleotide polymorphisms.

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