Fig. 2: Temporal trends in the prevalence of obesity, prediabetes/type 2 diabetes, impaired fasting glucose (IFG) and metabolic dysfunction-associated steatotic liver disease (MASLD) in 597 children with overweight/obesity who had their first obesity-related healthcare visit in different years.

Changes in sex distribution (OR for female sex 1.02, 95% CI 0.98–1.07, p = 0.349), median ages (r = −0.037, p = 0.373) and median BMI z-scores in different years of examination (2.47 [2002–4], 2.54 [2005–7], 2.36 [2008–10], 2.39 [2011–13], 2.46 [2014–16], 2.47 [2017–19], r = 0.005, p = 0.901) were not significant. Prediabetes was defined based fasting glucose or 2 h oral glucose tolerance test, utilizing cutoffs by the American Diabetes Association [3].