Table 2 Mean concentrations of urinary oxidative stress biomarkers in pregnant people by study visit.

From: Oxidative stress and fetal weight: observational findings from a pregnancy cohort in New York City

Concentration in urine (ng/m–1 [SD])

<18 weeks (ng/m–1 [SD])

18–25 weeks (ng/m–1 [SD])

>25 weeks (ng/m–1 [SD])

% below limits of detection (LOD)

Lipid

8-iso-prostaglandin F (8-iso-PGF2α)

0.26 (0.40)

0.27 (0.41)

0.27 (0.44)

30.4%

11β-prostaglandin F (11 − PGF2α)

0.24 (0.55)

0.27 (0.64)

0.24 (0.56)

54.3%

15(R)-prostaglandin F (15 − PGF2α)

0.37 (0.80)

0.40 (0.87)

0.42 (0.75)

32.2%

8-iso-15(R)-prostaglandin F (8,15 − PGF2α)

0.52 (0.89)

0.52 (0.75)

0.60 (0.88)

19.8%

Malondialdehyde (MDA)

21.0 (17.5)

21.4 (17.3)

20.7 (16.1)

0%

Protein

o,o′−dityrosine (diY)

1.36 (1.52)

1.74 (1.88)

1.68 (1.78)

2.5%

DNA

8−hydroxy−2′−deoxyguanosine (8−OHdG)

3.81 (3.32)

3.51 (7.07)

2.68 (2.61)

0.3%

  1. These concentrations were all further corrected for using the batch and timepoint-specific creatinine to account for minor biological (creatinine) and non-biological (laboratory) variations.