Table 3 Repeated-measures models of oxidative stress and estimated fetal weight at 36 weeks: moderation with time.

From: Oxidative stress and fetal weight: observational findings from a pregnancy cohort in New York City

Oxidative Stress Biomarker

Estimate at <18 weeks B grams (95% CI)

Estimate at 18–25 weeksa B grams (95% CI)

Estimate at >25 weeksa B grams (95% CI)

Lipid

8-iso-PGF2α

–0.02 (–1.3, 1.2)

–0.01 (–1.3, 1.3)

–0.03 (–1.3, 1.2)

11 − PGF2α

–0.02 (–1.0, 0.9)

–0.01 (–1.05, 1.03)

–0.06 (–1.1, 1.0)

15 − PGF2α

–0.06 (–1.2, 1.1)

–0.06 (–1.3, 1.2)

–0.03 (–1.2, 1.2)

8,15 − PGF2α

–0.07 (–1.2, 1.1)

–0.04 (–1.2, 1.1)

–0.03 (–1.2, 1.2)

MDA

0.04 (–3.1, 3.2)

0.04 (–3.4, 3.4)

0.09 (–3.1, 3.3)

Protein

diY

0.08 (–2.2, 2.4)

0.1 (–2.3, 2.5)

0.08 (–2.4, 2.5)

DNA

8−OHdG

–0.02 (–3.4, 3.4)

–0.07 (–3.0, 2.9)

–0.03 (–3.3, 3.3)

  1. Generalized estimating equations with an interaction term defined for exposure and exposure timing to assess associations between repeated measures of oxidative stress and estimated fetal weight at 36 weeks. All oxidative stress biomarkers are corrected for creatinine and log-transformed. Full oxidative stress biomarker names are provided in Table 2. Models adjusted for: pregnant person’s age, race, ethnicity, partnership status, education, smoking, insurance, parity, fetal sex, pre-pregnancy BMI, laboratory assay batch.
Back to article page