Table 2 Effect of rs9344 genotype on CCND1 expression stratified by t(11;14) status.
From: Functional variant rs9344 at 11q13.3 regulates CCND1 expression in multiple myeloma with t(11;14)
t(11;14) | Gt. | CoMMpass | Mayo | ||||
|---|---|---|---|---|---|---|---|
Freq. | Coe. (95% CI)a | p valuea | Freq. | Coe. (95% CI)a | p valuea | ||
No | AA | 105 | Ref. | Ā | 108 | Ref. | Ā |
No | GGā|āAG | 458 | ā3.56 (ā16.44ā9.32) | 0.59 | 414 | ā0.53 (ā8.23ā7.18) | 0.89 |
Yes | AA | 11 | 162.13 (124.83ā199.43) | 9.0āĆā10ā17 | 14 | 100.58 (80.34ā120.82) | 4.3āĆā10-21 |
Yes | GGā|āAG | 124 | 195.58 (179.84ā211.32) | 4.1āĆā10ā95 | 125 | 117.48 (108.1ā126.85) | 3.5āĆā10-95 |