Fig. 1: Age- and disease-related spectrum of somatic mutations at diagnosis.

The frequency of patients with mutations according to age and disease (A) CML and (B) Ph+ ALL. Patients were divided into subgroups based on age at diagnosis: children (0–17 years), AYA (18–39 years), and adults (>40 years). Spectrum of somatic mutations in (C) CML and (D) Ph+ ALL patients according to age subgroups. The total number of mutations identified is shown in tables.