Fig. 5: Clinical impact of ATM aberrations in Binet A CLL patients stratified by IGHV somatic hypermutation status. | Leukemia

Fig. 5: Clinical impact of ATM aberrations in Binet A CLL patients stratified by IGHV somatic hypermutation status.

From: ATM aberrations in chronic lymphocytic leukemia: del(11q) rather than ATM mutations is an adverse-prognostic biomarker

Fig. 5

Kaplan-Meier survival analysis using TTFT in Binet stage A in (A) U-CLL and (B) M-CLL patients. Pairwise comparisons were performed using the Cox–Mantel log-rank test. C Multivariable analysis using TTFT in Binet stage A CLL patients with U-CLL and M-CLL. U-CLL, CLL with unmutated IGHV genes, M-CLL, CLL with mutated IGHV genes. CI95, 95% confidence interval; * indicates a p value < 0.05, ** p < 0.01, and *** p < 0.001.

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