Fig. 2: Kaplan-Meier analysis of molecular relapse–free survival (MRFS) in the ENDURE trial. | Leukemia

Fig. 2: Kaplan-Meier analysis of molecular relapse–free survival (MRFS) in the ENDURE trial.

From: Randomized phase 3 trial of Ropeginterferon alfa-2b versus surveillance after tyrosine kinase inhibitor discontinuation in chronic myeloid leukemia (ENDURE/CML-IX)

Fig. 2

MRFS probabilities are shown for patients with CML who discontinued TKI therapy after one month and were randomized to receive either ropeginterferon alfa-2b (ropeg-IFN) maintenance for 15 months or surveillance. At months 7, 13, and 25 after randomization (corresponding to 6, 12, and 24 months after TKI discontinuation), MRFS probabilities were 73%, 64%, and 56% in the ropeg-IFN arm and 67%, 60%, and 59% in the surveillance arm, respectively. Numbers below the graph indicate patients at risk at each time point. CI confidence interval, HR hazard ratio.

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