Fig. 8: Confocal in vivo images of an anesthetized mouse beneath the laparoscopic-type probe. | Microsystems & Nanoengineering

Fig. 8: Confocal in vivo images of an anesthetized mouse beneath the laparoscopic-type probe.

From: Handheld endomicroscope using a fiber-optic harmonograph enables real-time and in vivo confocal imaging of living cell morphology and capillary perfusion

Fig. 8

The probe obtained real-time imaging results while in contact with the target tissue. a–c Fluorescence images of the blood vessel from the bladder. ICG molecules inside the blood vessel were imaged (Visualizations 1, 2, and 3). d Stitched fluorescence image of dermal tissue in the ear skin. Hair follicles (asterisks) were observed. e Mouse skin in vivo imaging process with the handheld endomicroscopic probe (Visualization 4). f, g Fluorescence image of dermal tissue of the nude mouse after topically applying ICG on the skin. Adipose tissue is observed as a black space surrounded by a polygonal fluorescent line. Scale bars are 35 μm

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