This special issue highlights cutting-edge innovations in micro/nano-engineered platforms for microphysiological systems and organ-on-chip technology. It focuses on integrating microfabrication, biosensors, advanced in vitro organ models, and artificial intelligence. By bridging in vitro and in vivo models, these systems enable precise disease modeling, drug discovery, and personalized medicine. The issue explores the intersection of advanced fabrication and real-world biomedical applications, providing a comprehensive overview of challenges and future directions, fostering collaboration to advance diagnostics, therapeutics, and disease research.

The development of micro- and nano-encapsulated delivery platforms has never been more urgent, given their far-reaching implications across biomedical and industrial applications. In biomedicine, these advanced platforms hold the potential to revolutionise drug delivery, regenerative medicine, and diagnostic technologies, enabling precise, controlled, and sustained release of therapeutics. However, despite significant progress, key challenges persist, including stability concerns, regulatory compliance, and sustainability. The reliance on synthetic polymers, often non-biodegradable and prone to leaching, raises environmental and safety concerns, necessitating the pursuit of innovative biomaterials. Furthermore, the high energy demands of current manufacturing processes call for more efficient and cost-effective alternatives. In response to these challenges, emerging bio-inspired and biomimetic approaches, biodegradable carriers, and smart-release mechanisms are paving the way for the next-generation of encapsulation systems. This special issue will critically examine the latest breakthroughs, offering a platform for novel insights into eco-friendly, scalable encapsulated platforms. We aim to foster cutting-edge technologies that will inspire the future of micro- and nanoencapsulation technologies in both biomedical and broader consumer applications.

Founded in 2017 by Microsystems & Nanoengineering (MINE), the MINE Young Scientists Forum is an annual academic exchange and recognition platform. It aims to identify and honor outstanding young researchers who have achieved remarkable results in cutting-edge scientific fields worldwide. Every year, the journal invites the winners of the Outstanding Young Scientist Award to submit their latest research papers, helping to showcase cutting-edge achievements and promote academic exchange and dissemination.

This special issue commemorates a decade of innovation and outstanding growth of Microsystems & Nanoengineering. It features cutting-edge research in Micro and Nano Electro Mechanical Systems, establishing a benchmark of the remarkable achievements made over the ten years.

High-performance microsystem technologies that can establish robust optical/electrical interfaces with implantable devices represent powerful tools in neuroscience research and clinical utility of importance. Of particular interest is biocompatible miniaturized design of integrated bioelectronics that offer sophisticated multi modal neuromodulation, including recording and stimulation of brain signals, and self-adaptive micro-/nano-engineering to the related brain tissues, at spatial scales from cellular resolution level to macroscopic area coverage. Specifically, this special issue focus on the bioelectronic devices as stable implants, with form factors that provide mechanical compliance with conformal contact to the soft, curved, and time-dynamic neural systems. Such techniques can serve as neural interfaces that communicate seamlessly with living biology, offering great potential use for diagnosis and treatments of associated neurological disorders.

Launched in 2017 by Microsystems & Nanoengineering (abbreviated as MINE), the MINE Young Scientists Forum is an annual academic exchange and recognition event. It aims to honor and identify outstanding young scientists worldwide who have made remarkable achievements through active exploration in cutting-edge scientific fields. Focusing on the core themes of "Micro/Nano Sensors and Actuators", "New Materials, Preparation and Packaging Technologies for Micro/Nano Devices", and "New Applications of Micro/Nano Systems", the MINE 2024 Young Scientists Forum is committed to building an academic exchange platform connecting young scientists globally. It strives to inspire new research ideas, support the growth of young academic talents, and inject more hopes and possibilities into scientific breakthroughs.

This special issue gives state-of-the-art Micro and Nano Technologies in the UK. The topic includes Micro and nano devices; Materials, fabrication, and packaging for micro and nano devices; Applied science of micro and nano devices. The top researchers in the UK will present their most valuable work in the abovementioned topics.

The Centrifugal Microfluidics Conference Special Issue is a curated collection of research papers selected from the inaugural International Conference on Centrifugal Microfluidics, held in April 2024 in Mexico City. This special issue, published in Microsystems & Nanoengineering, encompasses cutting-edge studies and advancements in centrifugal microfluidics, also known as Lab-on-a-Disc technology. The featured papers delve into the transformative potential of this technology across various sectors, addressing challenges and exploring applications in medical diagnostics, water treatment, and innovative microfluidic methodologies.

This Special Issue serves as a comprehensive platform to showcase research and technological breakthroughs in the field of MEMS packaging solutions and advanced testing methodologies that address the evolving challenges in MEMS device development.

This Special Issue aims to provide to the readers the latest innovations and developments on all aspects of Micro and Nano Electro Mechanical Systems from fundamental to applied research in the field of Guangdong - Hong Kong - Macao Greater Bay Area.

See what readers worldwide have been citing and sharing. In this web, we highlight a selection of articles, which top the list of the journal’s most downloaded and most shared (including press coverage, blogs, Twitter, Facebook and WeiChat). They showcase the breadth of scope and coverage that the journal consistently delivers to its readers.

Microsystems & Nanoengineering (MINE) Young Scientists Forum is an annual academic exchange and evaluation event launched by Microsystems & Nanoengineering in 2017 to recognize and discover global young scientists active in cutting-edge scientific areas who have made remarkable contributions. Focusing on topics of “micro/nano sensors and actuators”, “new materials, preparation methods and packaging technologies of micro/nano devices”, “new applications of micro/nano systems”, the 2023 MINE Young Scientists Forum aims to provide an academic exchange platform to connect global young scientists, inspire new ideas for scientific research, support the growth of young academic talents, and bring more hopes and possibilities to scientific breakthroughs.