Fig. 4: Phenotype assessment of OC spheroids. | Microsystems & Nanoengineering

Fig. 4: Phenotype assessment of OC spheroids.

From: A microfluidic platform for cultivating ovarian cancer spheroids and testing their responses to chemotherapies

Fig. 4: Phenotype assessment of OC spheroids.

a A representative spheroid from a microfluidic device stained for an epithelial marker EpCAM and a proliferation marker Ki-67 as well as the nuclear dye DAPI. b PCR-RT results for the proliferation marker Ki-67 and epithelial markers PAX8, CK-7, and EpCAM. The results show similar or higher expression levels in microfluidic cultures compared to the standard culture method (p < 0.05, n = 3)

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