Fig. 2: Illustration of the proposed Rubik’s cube-like microfluidic system.

a Overall illustration of the cube. b Corner blocks of the microfluidic cube, including three-way inlets/outlets (left), 3D T-junction(middle). and turning (right). c Edge blocks of the microfluidic cube, from left to right are the straight channel, spiral channel, 3D chamber, and planar chamber, respectively. d Central block and other components of the cube