Fig. 5: Mixing efficiency of a food dye (Inlet B) with water (Inlet A). | Microsystems & Nanoengineering

Fig. 5: Mixing efficiency of a food dye (Inlet B) with water (Inlet A).

From: Systematic characterization of cleanroom-free fabricated macrovalves, demonstrating pumps and mixers for automated fluid handling tuned for organ-on-chip applications

Fig. 5

a Schematic top-view of the device with an indication of the site where the intensity was measured. b Image of the channel before mixing. Channel width (indicated with the dashed lines) is 1 mm. c Image of the channel after mixing. Please note that this channel is rounded. Therefore, the intensity at the corners is lower, while the actual concentration is constant; see Supplementary information S.7 for the corresponding calibration.d Mixing efficiency over time. The periods of mixing and afterward flushing are indicated. After 17 s of mixing, the mixing efficiency approaches 90%. e, f Calculated concentration along the width of the channel (distance x) before (e) and after (f) mixing. An average mixing efficiency of 90.4 ± 3.32% was observed after 17 s of mixing (n = 3). Dilution of 100% food dye (Inlet B) with water (Inlet A). g Schematic top-view of the device with an indication (red box) of the site where the intensity was measured. h Image of the mixing and metering device at the start of the experiment. i Calculated concentration of the food dye in the channel after diluting 100% food dye with water for 5 cycles. An exponential decrease in food dye concentration is observed with an exponential fit of y = 102.69e−0.561x with R2 = 0.999 (n = 3 measurements)

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