Table 2 Geometry design principles of passive and label-free microfluidics
Designing principles | Subprinciples | Examples |
|---|---|---|
Shape modification | Parametric optimization | DLD pillar size and gap optimization |
IMF/VEM rectangular cross section modification | ||
Shape optimization | DLD pillar shape optimization | |
IMF channel direction modification | ||
IMF channel cross section shape optimization | ||
Topology modification | Structural simplification | Simplified DLD |
Topology optimization | Topology-optimized DLD pillar | |
Topology-optimized IMF channel | ||
Combination | Combination within the same scheme | Cascaded/mirrored DLD array |
Duplicated PFF | ||
Combination of spiral and serpentine IMF channels | ||
Combination of different schemes | DLD array before an IMF focusing channel | |
IMF channel before a DLD array | ||
DLD array with viscoelastic fluid | ||
3D structure | 3D structure | 3D DLD |
3D IMF channel | ||
Top and bottom wall modification | Hydrophoresis |
