Fig. 1: Drug screening at the single-cell level based on multiconcentration gradient construction and a single-cell capture device.
From: Construction of multiple concentration gradients for single-cell level drug screening
a Schematic diagram of the integrated microfluidic device. b The detailed design of a single-cell capture device. The various channels are shown with different colors to visualize the microfluidic device’s different components. Red and green indicate the fluidic channels of cells and reagents, respectively, and blue shows the control channels and valves. c Schematic of manipulation of single-cell capture according to cell size and deformability. The procedure consists of three steps: cell infusion, single-cell capture, and reagent infusion
