Fig. 5: Seal resistance, extracellular action potential (EAP) signal-to-noise ratio (SNR) and their comparison for primary rodent cortex neurons after 16 days in culture.
From: Impedance spectroscopy of the cell/nanovolcano interface enables optimization for electrophysiology
a Seal resistance of neurons on nanovolcanoes of different geometries. Groups (i–vi) are as in Fig. 4. b Average SNR of spontaneous EAP measured from neurons on nanovolcanoes of different geometries. In (a) and (b), each data point corresponds to a single cell, and the boxplots summarize the sample distribution for a given geometry. c Plot of the average EAP SNRs against seal resistances for all cells. The line is a linear regression characterized by the equation at the top of the plot, Pearson coefficient r and coefficient of determination R2. d Same as in (c) but only for cells whose average EAP SNRs were above 20. p-values correspond to a two-sided Mann‒Whitney U-test
