Fig. 2: Experimental system and experimental flow chart.
From: Strain sensor on a chip for quantifying the magnitudes of tensile stress on cells
a A schematic of the components of the stain-sensor-on-chip. The injection valve is connected through the gas pipe and controls the uniform extraction and perfusion of gas in the vacuum chamber. The chip-integrated sensor connects to the external circuit to obtain signals and displays the deformation size of the sensitive area inside the chip through the oscilloscope. The chip can be placed above the objective lens of the microscope for observations. b Chip manufacturing process: Step 1, the use of soft lithography technology to manufacture the SU-8 mold; Step 2, curing according to the proportion of PDMS in the mold; Step 3, plasma treatment; Step 4, Galinstan injection into the liquid channel; Step 5, cells and culture medium injection, into the cell culture. c Cross-sectional diagram of the chip: the cell culture chamber layer, liquid metal layer, and vacuum chamber layer from top to bottom
