Fig. 6: A schematic of the strain sensor on a chip.
From: Strain sensor on a chip for quantifying the magnitudes of tensile stress on cells
a Using organ-on-a-chip for cultured cardiomyocytes. The chip integrates a vacuum chamber to apply tensile stress to the cells to mimic the microenvironment in vivo; integrated sensor feedback quantifies cell deformation. b A cell culture layer, a liquid metal layer, a thin film layer, and a vacuum chamber layer can be assembled into an integrated chip that contains three microfluidic channels: a vacuum chamber, a liquid metal injection channel, and a cell culturing chamber. c Schematic diagram of a prestretch (left) and poststretch (right) stretch device. The diagram shows the cross-section and the working mechanism of the chip. When vacuum pressure is applied to the annular vacuum chamber, the wall of the annular vacuum chamber deflects outward, stretching the internal suspended film and the adherent cells on it. The cells on the membrane are stretched and relaxed repeatedly
