Fig. 4: Microfluidics for drug screening and disease modeling.
From: Microfluidic platforms for monitoring cardiomyocyte electromechanical activity
a Microfibrous scaffolds for evaluating cardiovascular toxicity in the engineered endothelialized myocardium. Reproduced with permission from ref.114. b Cardiac microphysiological system containing nutrient channels and cell channels. Reproduced with permission from ref.112. c Heart-on-a-chip for studying the effects of acute hypoxia on cardiac function. Reproduced with permission from ref.129. d Microfluidic myocardium-on-a-chip for CMs and ECs cocultured with capillary-like channels. Reproduced with permission from ref.113. e Microfluidic device integrated with CMs and liver cancer cells to simulate the side effects of the anticancer drug doxorubicin (DXR). Reproduced with permission from ref.115
