Fig. 5: Microfluidic platform design strategies for monitoring the physiological signals of cardiomyocytes.
From: Microfluidic platforms for monitoring cardiomyocyte electromechanical activity
a Microfluidic device for hiPSC-CM purification comprising a peristaltic pump, cell suspension reservoirs, and a serpentine channel. Reproduced with permission from ref.137. b Microfluidic device for electrophysiological cell sorting in response to stimuli. Reproduced with permission from ref.138. c Heart-on-a-chip providing mechanical and biochemical costimulation. Reproduced with permission from ref.143. d Perfusable system connected with a heart-on-a-chip for measuring myocardial‒microvascular interactions. Reproduced with permission from ref.145. e Microfluidic platform fabricated by DLW lithography and soft lithography for monitoring oscillatory forces generated by microtissues under a prescribed mechanical loading and pacing. Reproduced with permission from ref.146
