Fig. 1: Overview of multiplexed dose delivery for efficient CAP dose optimization.

a The critical role of CAP dose in eliciting different cell behaviors. b Schematic of the conventional single-dose, single-sample treatment modality by a plasma jet device. c Experimental design for a small-scale test utilizing a plasma jet device. d, e Conceptual framework of multiplexed dose delivery with fluidic manipulation. f Experimental design for a typical small-scale test utilizing the multiplexed treatment device. g Significance of the multiplexed dose delivery device in reducing experiment cycles with increased candidate samples (e.g., three candidate doses and four repetitions per experiment)