Table 3b Multivariate regression model for predictors of systemic metastasis and tumor related deaths (Only variables that predicted DSS and MFS on a univariate model were included in the multivariate regression analysis)
From: Quasimesenchymal phenotype predicts systemic metastasis in pancreatic ductal adenocarcinoma
MFS (P) multivariate | HR (95% CI) | DSS (P) multivariate | HR (95% CI) | |
|---|---|---|---|---|
SMAD4 loss vs. SMAD4 wild type | 0.001 | 2.815 (1.586–4.998) | 0.025 | 1.645 (1.065–2.543) |
Quasi-mesenchymal vs. epithelial | 0.0001 | 10.041(4.998–24.752) | 0.048 | 1.597 (1.004–2.542) |
Lymph node status N1 vs N0 | 0.930 | 0.955 (0.340–2.802) | 0.416 | 1.421 (0.610–3.313) |
Stage | 0.488 | 1.309 (0.612–2.802) | 0.301 | 1.381 (0.749–2.544) |
No chemotherapy vs. chemotherapy | 0.001 | 4.296 (2.023–9.125) | ||
Size > 2 vs. <2 cm | 0.038 | 2.103 (1.042–4.242) |