Table 3b Multivariate regression model for predictors of systemic metastasis and tumor related deaths (Only variables that predicted DSS and MFS on a univariate model were included in the multivariate regression analysis)

From: Quasimesenchymal phenotype predicts systemic metastasis in pancreatic ductal adenocarcinoma

 

MFS (P) multivariate

HR (95% CI)

DSS (P) multivariate

HR (95% CI)

SMAD4 loss vs. SMAD4 wild type

0.001

2.815 (1.586–4.998)

0.025

1.645 (1.065–2.543)

Quasi-mesenchymal vs. epithelial

0.0001

10.041(4.998–24.752)

0.048

1.597 (1.004–2.542)

Lymph node status N1 vs N0

0.930

0.955 (0.340–2.802)

0.416

1.421 (0.610–3.313)

Stage

0.488

1.309 (0.612–2.802)

0.301

1.381 (0.749–2.544)

No chemotherapy vs. chemotherapy

0.001

4.296 (2.023–9.125)

  

Size > 2 vs. <2 cm

  

0.038

2.103 (1.042–4.242)

  1. MFS metastasis free survival, HR hazards ratio, CI confidence interval, DSS disease specific survival, N0 no lymph node involvement, N1 lymph node involvement