Fig. 7: Kaplan–Meier curves illustrating disease-free survival (DFS) of patients suffering from salivary duct carcinoma (SDCa).

a DFS of patients according to their smoking history. Moderate smokers had consumption of 1–50 pack years. Heavy smokers had consumption of >50 pack years. b DFS based on gender c) DFS according to TP53 mutations status. Loss of function mutations is defined as frameshift, splice site, or nonsense mutations. d Association of MYC amplification and DFS. e Association pathogenic alterations (mutations or copy number variations) in genes of the cell cycle pathway (CCND1, CCND2, CCND3, CCNE1, CDK4, CDK6, CDKN2A, RB1), and DFS. f Association of DFS with subgroups of SDCa based on ERBB2 and AR status, adjusted for effects of gender and the cell cycle pathway.