Fig. 3: Event-free proportion at 5 years for MS-status, CMS, and Immunoscore in non-pedunculated T1 CRCs. | Modern Pathology

Fig. 3: Event-free proportion at 5 years for MS-status, CMS, and Immunoscore in non-pedunculated T1 CRCs.

From: Associations of non-pedunculated T1 colorectal adenocarcinoma outcome with consensus molecular subtypes, immunoscore, and microsatellite status: a multicenter case-cohort study

Fig. 3

5-year event-free proportion curves for adverse outcome based on the case-cohort dataset, reweighted to full cohort proportion by taking the random subgroup sampling fraction into account for (a) MSI (CMS1) vs. MSS (CMS2/3/4) tumors (b) CMS4 vs CMS1/2/3 tumors (c) I-low (≤25th percentile) vs. I-high (>25th percentile). Multivariable HR adjusted for conventional histologic risk factors (differentiation grade, lymphovascular invasion, submucosal invasion depth, and tumor budding). HR Hazard Ratio as calculated with Prentice’s method; MSI microsatellite instable, MSS microsatellite stable, CMS Consensus Molecular Subtype, I-low Immunoscore Low, I-high Immunoscore High.

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